1-benzyl 4-ethyl 4-methylpiperidine-1,4-dicarboxylate

1-benzyl 4-ethyl 4-methylpiperidine-1,4-dicarboxylate - Names and Identifiers

Name	N-Cbz-4-Methylisonipecotic acid ethyl ester
Synonyms	N-Cbz-4-Methylisonipecotic acid ethyl ester N-Cbz-4-Methyl Isonipecotic Acid Ethyl Ester 1-benzyl 4-ethyl 4-methylpiperidine-1,4-dicarboxylate 4-Methyl-1,4-piperidinedicarboxylic acid 4-ethyl 1-(phenylmethyl) ester 1,4-Piperidinedicarboxylic acid, 4-methyl-, 4-ethyl 1-(phenylmethyl) ester
CAS	203521-95-3
InChI	InChI=1/C17H23NO4/c1-3-21-15(19)17(2)9-11-18(12-10-17)16(20)22-13-14-7-5-4-6-8-14/h4-8H,3,9-13H2,1-2H3

1-benzyl 4-ethyl 4-methylpiperidine-1,4-dicarboxylate - Physico-chemical Properties

Molecular Formula	C17H23NO4
Molar Mass	305.37
Density	1.137
Storage Condition	2-8°C
Refractive Index	1.525

1-benzyl 4-ethyl 4-methylpiperidine-1,4-dicarboxylate - Introduction

N-Cbz-4-Methylisonipecotic acid ester is an organic compound with the chemical formula C22H25NO3. The following is an introduction to the nature, use, formulation and safety information of N-Cbz-4-Methylisonipecotic acid ethyl ester:

Nature:
N-Cbz-4-Methylisonipecotic acid ester is a white solid, soluble in organic solvents such as ether, dimethylformamide and methanol. It is sensitive to air and humidity and should be stored in a dry place.

Use:
N-Cbz-4-Methylisonipecotic acid ethyl ester is commonly used in protecting groups and intermediates in chemical synthesis. It can be used to protect the amine groups to prevent unwanted side reactions in chemical reactions. In addition, it can also be used as an amination reagent in organic synthesis.

Method:
N-Cbz-4-Methylisonipecotic acid ethyl ester can be prepared by reacting 4-methyl-4-piperidinecarboxylic acid with a chloroformylating reagent (such as chloroformyl chloride). The reaction is typically carried out under an inert atmosphere using a base catalyst such as triethylamine. The obtained product can be purified by crystallization or column chromatography.

Safety Information:
Appropriate security measures need to be taken when operating and storing N-Cbz-4-Methylisonipecotic acid ethyl ester. It is a chemical that may have irritating effects on the skin, eyes and respiratory system. Avoid contact with skin and eyes, and wear protective gloves and glasses if necessary. In addition, it should be stored in a cool, dry place, away from fire and oxidizing agents.

Last Update：2024-04-10 22:29:15